Comparison · NCT00513500-9119a76c
Enhanced Treatment vs Current Practice: Number of Children Who do Not Respond to Treatment for Pneumonia
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Enhanced Treatment vs Current Practice: Number of Children Who do Not Respond to Treatment for Pneumonia. Trial comparisons, record NCT00513500-9119a76c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00513500-9119a76c
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.113 | 0.0846 | 0.15 | wilson | |
| Risk in group 2 | 0.202 | 0.153 | 0.262 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0887 | -0.156 | -0.0271 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.561 | 0.377 | 0.834 | log | |
| Odds ratio, group 1 over group 2 | 0.505 | 0.315 | 0.809 | log | |
| Number needed to treat, for one fewer participant with the outcome on Enhanced Treatment than on Current Practice | 11.3 | 6.42 | 36.9 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Enhanced Treatment | Intervention: Treatment for malaria and pneumonia:~Treat malaria based on rapid diagnostic test with half tablet (20mg artemether, 120mg lumefantrine) for children weighing 5-9.9kg and one tablet (20mg artemether, 120mg lumefantrine) for children weighing 10-20kg twice a day for three days.~Treat pneumonia with half tablet (250mg amoxicillin) for children weighing 5 - 9.9kg and one tablet (250mg amoxicillin for children weighing 10-20kg three times a day for five days. | 41 | 362 | OG000 |
| Group 2 | Current Practice | Control: Treatment for malaria and pneumonia referral Treat malaria based on fever with half tablet (20mg artemether, 120mg lumefantrine) for children weighing 5-9.9kg and one tablet (20mg artemether, 120mg lumefantrine) for children weighing 10-20kg twice a day for three days.~Refer children with pneumonia to the nearest health facility. | 41 | 203 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Children Who do Not Respond to Treatment for Pneumonia
- Description
- Time frame
- one year
- Population
- Based on number classified as having pneumonia. Analysis was per intention to treat
Source ClinicalTrials.gov
Trial
- Title
- Zambia Integrated Management of Malaria and Pneumonia Study
- NCT number
- NCT00513500
- Phases
- NA
- Conditions
- Pneumonia, Malaria
- Interventions
- Coartem and amoxicillin, Coartem
- Lead sponsor
- Boston University
- Results first posted
- 2010-07-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00513500?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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