Comparison · NCT00564629-sae
Oral Acetaminophen (PO APAP) 1 g vs Intravenous Acetaminophen (IV APAP) 1 g / 100 ml Solution: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Oral Acetaminophen (PO APAP) 1 g vs Intravenous Acetaminophen (IV APAP) 1 g / 100 ml Solution: serious adverse events. Trial comparisons, record NCT00564629-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00564629-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0 | 0 | 0.07 | wilson | |
| Risk in group 2 | 0 | 0 | 0.0664 | wilson | |
| Risk difference, group 1 minus group 2 | 0 | -0.0664 | 0.07 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to harm | from the risk difference interval | the two groups' risks are equal |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Oral Acetaminophen (PO APAP) 1 g | group of subjects randomly selected to receive 1 g of oral acetaminophen as the study treatment | 0 | 51 | EG000 |
| Group 2 | Intravenous Acetaminophen (IV APAP) 1 g / 100 ml Solution | group of subjects randomly selected to receive 1 g /100 ml of intravenous acetaminophen solution as the study treatment | 0 | 54 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Treatment Emergent Adverse Events(TEAEs)were reported from T0 (on or after the start of study medication) to 6 hours after study medication was administered to the subject.
Source ClinicalTrials.gov
Trial
- Title
- Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult Males
- NCT number
- NCT00564629
- Phases
- PHASE3
- Conditions
- Fever
- Interventions
- Intravenous acetaminophen plus oral placebo, Oral acetaminophen plus IV placebo, Reference standard endotoxin (RSE)
- Lead sponsor
- Mallinckrodt
- Results first posted
- 2010-09-21
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00564629?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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