Comparison · NCT00590967-sae
Treatment Group 1 (IMRT, Brachytherapy, Cisplatin) vs Treatment Group 2 (IMRT, Brachytherapy, Cisplatin): serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Treatment Group 1 (IMRT, Brachytherapy, Cisplatin) vs Treatment Group 2 (IMRT, Brachytherapy, Cisplatin): serious adverse events. Trial comparisons, record NCT00590967-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00590967-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.244 | 0.138 | 0.393 | wilson | |
| Risk in group 2 | 0.2 | 0.0807 | 0.416 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0439 | -0.197 | 0.235 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.22 | 0.436 | 3.41 | log | |
| Odds ratio, group 1 over group 2 | 1.29 | 0.349 | 4.77 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Treatment Group 1 (IMRT, Brachytherapy, Cisplatin) than on Treatment Group 2 (IMRT, Brachytherapy, Cisplatin) | 22.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Treatment Group 1 (IMRT, Brachytherapy, Cisplatin) | Pelvic Lymph Nodes Only Positive on FDG PET.~IMRT External Beam radiation to the para-aortic region (45 Gy)~Pelvis intracavitary brachytherapy (6 HDR treatments)~Weekly cisplatin (40 mg/m\^2) | 10 | 41 | EG000 |
| Group 2 | Treatment Group 2 (IMRT, Brachytherapy, Cisplatin) | Para-Aortic Lymph Nodes Positive on FDG PET~IMRT (50.4 Gy to para-aortic lymph node bed with a 10.8 Gy boost to nodes)~IMRT external beam pelvic radiation therapy as appropriate for stage~Intracavitary brachytherapy (6 HDR treatments)~Weekly cisplatin (40 mg/m\^2) | 4 | 20 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- A Phase II Study of Extended Field IMRT External Beam Irradiation and Intracavitary Brachytherapy
- NCT number
- NCT00590967
- Phases
- PHASE2
- Conditions
- Cervical Cancer
- Interventions
- IMRT extended field external beam radiation therapy, Brachytherapy, Cisplatin
- Lead sponsor
- Washington University School of Medicine
- Results first posted
- 2016-08-29
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00590967?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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