1 Progressive Resistance Training vs 2 Modified Fitness Counts: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.32 | 0.172 | 0.516 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.231 | 0.11 | 0.421 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.0892 | -0.151 | 0.319 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.39 | 0.561 | 3.43 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.57 | 0.454 | 5.42 | log | ClinicalTrials.gov | |
| Number needed to harm, for one more participant with a serious adverse event on 1 Progressive Resistance Training than on 2 Modified Fitness Counts | 11.2 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | 1 Progressive Resistance Training | Subjects performed between 60 and 90 minutes of progressive resistance training two times a week for two years at a local gym. These sessions were supervised by a personal trainer two times a week for the first six months of training and then once a week for the remaining 18 months of training.~Exercises included progressive resistance training. Participants exercised twice a week for 2 years doing progressive resistance training. | 8 | 25 | EG000 | ClinicalTrials.gov |
| Group 2 | 2 Modified Fitness Counts | Subjects performed between 60 and 90 minutes of flexibility training two times a week for two years at a local gym. These sessions were supervised by a personal trainer two times a week for the first six months of training and then once a week for the remaining 18 months of training.~Exercise inlcuded flexibility training. Participants exercised twice a week for 2 years doing flexibility training. | 6 | 26 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | SAE's and AE's were collected for 2 years for each study participant. | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | The Effect of Exercise on Individuals With Parkinson's Disease | ClinicalTrials.gov |
| NCT number | NCT00591344 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Parkinson's Disease | ClinicalTrials.gov |
| Interventions | Progressive resistance training, Modified Fitness Counts | ClinicalTrials.gov |
| Lead sponsor | University of Illinois Chicago | ClinicalTrials.gov |
| Results first posted | 2015-02-09 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT00591344?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.