Comparison · NCT00619918-321cc3c0
Nebulized 3% Saline vs Nebulized 0.9% Saline: Number of Participants With Supplemental Medication Use
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Nebulized 3% Saline vs Nebulized 0.9% Saline: Number of Participants With Supplemental Medication Use. Trial comparisons, record NCT00619918-321cc3c0. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00619918-321cc3c0
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.169 | 0.126 | 0.222 | wilson | |
| Risk in group 2 | 0.181 | 0.135 | 0.237 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0117 | -0.0828 | 0.0587 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.935 | 0.625 | 1.4 | log | |
| Odds ratio, group 1 over group 2 | 0.922 | 0.566 | 1.5 | log | |
| Number needed to treat, for one fewer participant with the outcome on Nebulized 3% Saline than on Nebulized 0.9% Saline | 85.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Nebulized 3% Saline | 3% NaCl, 4 mL inhalation, up to 3 inhalations every 20 minutes in the ED, and Q8H in the inpatient setting.~Nebulized 3% saline: 4 ml inhaled q8h | 39 | 231 | OG000 |
| Group 2 | Nebulized 0.9% Saline | 0.9% NaCl, 4 mL inhalation, up to 3 inhalations every 20 minutes in the ED, and Q8H in the inpatient setting.~Nebulized 0.9% saline: normal saline | 39 | 216 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Supplemental Medication Use
- Description
- patients who received supplemental albuterol, ipratropium, or epinephrine inhaled treatment (other than pre-treatment for study med)
- Time frame
- 14 days
- Population
230 patients were allocated to the 3% group; one patient allocated to the 0.9% group received 3% so was added to the 3% group for analysis, totaling 231 patients. The 0.9% group originally had 217 patients but after moving this patient to the 3% group, there are now 216 patients in the 0.9% group.
Source ClinicalTrials.gov
Trial
- Title
- Nebulized Hypertonic Saline for Bronchiolitis
- NCT number
- NCT00619918
- Phases
- PHASE2, PHASE3
- Conditions
- Bronchiolitis
- Interventions
- Nebulized 3% saline, Nebulized 0.9% saline
- Lead sponsor
- Children's Hospital Los Angeles
- Results first posted
- 2013-10-10
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00619918?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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