Comparison · NCT00627393-sae
Granulocyte Arm vs Control Arm: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Granulocyte Arm vs Control Arm: serious adverse events. Trial comparisons, record NCT00627393-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00627393-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.464 | 0.34 | 0.593 | wilson | |
| Risk in group 2 | 0.431 | 0.312 | 0.559 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0333 | -0.145 | 0.209 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.08 | 0.716 | 1.62 | log | |
| Odds ratio, group 1 over group 2 | 1.14 | 0.546 | 2.39 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Granulocyte Arm than on Control Arm | 30.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Granulocyte Arm | Received G-CSF/dexamethasone-mobilized granulocyte transfusions in addition to antimicrobial therapy. | 26 | 56 | EG001 |
| Group 2 | Control Arm | Received antimicrobial therapy alone. | 25 | 58 | EG000 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Serious adverse events were reported up to 42 days after randomization.
Source ClinicalTrials.gov
Trial
- Title
- Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study)
- NCT number
- NCT00627393
- Phases
- PHASE3
- Conditions
- Neutropenia, Infection
- Interventions
- Standard antimicrobial therapy, Granulocyte transfusions, G-CSF/dexamethasone, Apheresis machine
- Lead sponsor
- Carelon Research
- Results first posted
- 2014-12-23
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00627393?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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