Comparison · NCT00665561-deaths
Maraviroc Exposed vs Maraviroc Unexposed: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Maraviroc Exposed vs Maraviroc Unexposed: deaths from any cause. Trial comparisons, record NCT00665561-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00665561-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.057 | 0.0457 | 0.0709 | wilson | |
| Risk in group 2 | 0.0699 | 0.0565 | 0.0863 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0129 | -0.0328 | 0.0064 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.815 | 0.6 | 1.11 | log | |
| Odds ratio, group 1 over group 2 | 0.804 | 0.58 | 1.11 | log | |
| Number needed to treat, for one fewer death from any cause on Maraviroc Exposed than on Maraviroc Unexposed | 77.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Maraviroc Exposed | Human immunodeficiency virus- 1( HIV-1) infected, treatment-experienced adult participants, who were prescribed with maraviroc along with an optimized background antiretroviral therapy (OBT) regimen (in usual clinical practice following the approved local label of maraviroc), were included in this study and were observed in this study for an observation period of up to 5 years following enrollment. | 75 | 1,316 | EG000 |
| Group 2 | Maraviroc Unexposed | HIV-1 infected, treatment-experienced adult participants, who were not prescribed with maraviroc but with OBT regimen (in usual clinical practice following the approved local label of maraviroc), were included in this study and were observed in this study for an observation period of up to 5 years following enrollment. | 79 | 1,130 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Up to 5 years following enrollment
Source ClinicalTrials.gov
Trial
- Title
- Prospective Observational Epidemiologic Study of Maraviroc's Safety
- NCT number
- NCT00665561
- Phases
- Conditions
- Human Immunodeficiency Virus
- Interventions
- Maraviroc along with an optimized background antiretroviral drug regimen, Optimized background antiretroviral drug regimen without maraviroc
- Lead sponsor
- ViiV Healthcare
- Results first posted
- 2020-04-07
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00665561?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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