Comparison · NCT00690794-sae
Travoprost vs Latanoprost: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Travoprost vs Latanoprost: serious adverse events. Trial comparisons, record NCT00690794-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00690794-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0138 | 0.0059 | 0.0318 | wilson | |
| Risk in group 2 | 0.0193 | 0.00937 | 0.0393 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00551 | -0.027 | 0.0151 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.714 | 0.229 | 2.23 | log | |
| Odds ratio, group 1 over group 2 | 0.71 | 0.223 | 2.26 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Travoprost than on Latanoprost | 182 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Travoprost | One drop self-administered in the study eye(s) once daily for 90 days | 5 | 363 | EG000 |
| Group 2 | Latanoprost | One drop self-administered in the study eye(s) once daily for 90 days | 7 | 363 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Adverse events were collected for the duration of the study: 03 July 2008 to 26 May 2009.
Source ClinicalTrials.gov
Trial
- Title
- Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertension
- NCT number
- NCT00690794
- Phases
- PHASE3
- Conditions
- Open-angle Glaucoma, Ocular Hypertension
- Interventions
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Lead sponsor
- Alcon Research
- Results first posted
- 2012-07-03
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00690794?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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