Comparison · NCT00718809-3dfc0972
Thymoma vs Thymic Carcinoma: Expected Toxicities Including Skin Rashes and Diarrhea
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Thymoma vs Thymic Carcinoma: Expected Toxicities Including Skin Rashes and Diarrhea. Trial comparisons, record NCT00718809-3dfc0972. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00718809-3dfc0972
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.833 | 0.552 | 0.953 | wilson | |
| Risk in group 2 | 0.333 | 0.121 | 0.646 | wilson | |
| Risk difference, group 1 minus group 2 | 0.5 | 0.0795 | 0.744 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.5 | 0.959 | 6.52 | log | |
| Odds ratio, group 1 over group 2 | 10 | 1.28 | 78.1 | log | |
| Number needed to treat, for one more participant with the outcome on Thymoma than on Thymic Carcinoma | 2 | 1.34 | 12.6 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Thymoma | Patients classified as having Thymoma. Patients receive 175 mg oral saracatinib once daily on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. | 10 | 12 | OG000 |
| Group 2 | Thymic Carcinoma | Patients classified as having Thymic carcinoma. Patients receive 175 mg oral saracatinib once daily on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. | 3 | 9 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Expected Toxicities Including Skin Rashes and Diarrhea
- Description
- Number of patients who had toxicities classified as skin rashes and diarrhea within the adverse events.
- Time frame
- Up to 5 years
- Population
- All patients
Source ClinicalTrials.gov
Trial
- Title
- Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic Cancer
- NCT number
- NCT00718809
- Phases
- PHASE2
- Conditions
- Invasive Thymoma and Thymic Carcinoma, Recurrent Thymoma and Thymic Carcinoma, Stage III Thymoma, Stage IVA Thymoma, Stage IVB Thymoma
- Interventions
- saracatinib
- Lead sponsor
- National Cancer Institute (NCI)
- Results first posted
- 2015-06-10
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00718809?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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