Comparison · NCT00726323-deaths
Intermittent 5 & 9 Dosing Regimen vs Daily Dosing Regimen: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Intermittent 5 & 9 Dosing Regimen vs Daily Dosing Regimen: deaths from any cause. Trial comparisons, record NCT00726323-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00726323-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.378 | 0.241 | 0.539 | wilson | |
| Risk in group 2 | 0.162 | 0.0765 | 0.311 | wilson | |
| Risk difference, group 1 minus group 2 | 0.216 | 0.0132 | 0.398 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.33 | 1.01 | 5.41 | log | |
| Odds ratio, group 1 over group 2 | 3.14 | 1.05 | 9.43 | log | |
| Number needed to harm, for one more death from any cause on Intermittent 5 & 9 Dosing Regimen than on Daily Dosing Regimen | 4.63 | 2.51 | 76 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intermittent 5 & 9 Dosing Regimen | Eligible participants received oral foretinib bisphosphate 240 mg on Days 1 to 5 of every 14-day cycle. Participants continued this schedule for 8 weeks. The treatment drug was supposed to be stopped any time in case of disease progression. All participants were followed-up every 8 weeks for tumor assessment, while the participant remained in the treatment extension period. | 14 | 37 | EG000 |
| Group 2 | Daily Dosing Regimen | Eligible participants received oral foretinib bisphosphate 80 mg daily of every 14-day cycle. Participants continued this schedule for 8 weeks. treatment drug was supposed to be stopped any time in case of disease progression. All participants were followed-up every 8 weeks for tumor assessment, while the participant remained in the treatment extension period. | 6 | 37 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Approximately up to 48 months
Source ClinicalTrials.gov
Trial
- Title
- A Phase II Study of GSK1363089 (Formerly XL880) for Papillary Renal-Cell Carcinoma (PRC)
- NCT number
- NCT00726323
- Phases
- PHASE2
- Conditions
- Carcinoma, Renal Cell
- Interventions
- foretinib (formerly GSK1363089 or XL880)
- Lead sponsor
- GlaxoSmithKline
- Results first posted
- 2017-12-11
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00726323?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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