Comparison · NCT00832091-421cc7d8
Thymosin Beta 4 (Tβ4) at 3 Doses vs Placebo: Wound Healing (Wound Closure Without Drainage) by Applying Tβ4 Gel Once Daily for up to 84 Days to Patients With Venous Stasis (VS) Ulcers
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Thymosin Beta 4 (Tβ4) at 3 Doses vs Placebo: Wound Healing (Wound Closure Without Drainage) by Applying Tβ4 Gel Once Daily for up to 84 Days to Patients With Venous Stasis (VS) Ulcers. Trial comparisons, record NCT00832091-421cc7d8. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00832091-421cc7d8
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.218 | 0.129 | 0.344 | wilson | |
| Risk in group 2 | 0.235 | 0.0956 | 0.473 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0171 | -0.27 | 0.171 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.927 | 0.344 | 2.5 | log | |
| Odds ratio, group 1 over group 2 | 0.907 | 0.25 | 3.3 | log | |
| Number needed to treat, for one fewer participant with the outcome on Thymosin Beta 4 (Tβ4) at 3 Doses than on Placebo | 58.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Thymosin Beta 4 (Tβ4) at 3 Doses | 0.01% Tβ4 weight by weight (w/w), 0.03% Tβ4 w/w, 0.1% Tβ4 w/w | 12 | 55 | OG001 |
| Group 2 | Placebo | 0.00% Thymosin Beta 4 (Tβ4), weight/weight (w/w) | 4 | 17 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Wound Healing (Wound Closure Without Drainage) by Applying Tβ4 Gel Once Daily for up to 84 Days to Patients With Venous Stasis (VS) Ulcers
- Description
- Wound healing effectiveness of Tβ4 gel applied once daily for up to 84 days to patients expressed as the number of patients whose wound had closed without drainage at the end of the study, Day 84
- Time frame
- Up to 84 days
- Population
- Analysis per protocol, Intent-to-treat (ITT), using Last Observation Carried Forward (LOCF)
Source ClinicalTrials.gov
Trial
- Title
- Study of Thymosin Beta 4 in Patients With Venous Stasis Ulcers
- NCT number
- NCT00832091
- Phases
- PHASE2
- Conditions
- Venous Stasis Ulcers
- Interventions
- Thymosin Beta 4, Placebo
- Lead sponsor
- RegeneRx Biopharmaceuticals, Inc.
- Results first posted
- 2010-03-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00832091?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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