Iron and Folate vs Multiple Micronutrient: Preterm Birth
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.218 | 0.211 | 0.225 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.186 | 0.18 | 0.193 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.0321 | 0.0225 | 0.0417 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.17 | 1.12 | 1.23 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.22 | 1.15 | 1.3 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on Iron and Folate than on Multiple Micronutrient | 31.1 | 24 | 44.4 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Iron and Folate | Iron (27 mg) and folic acid (600 ug)~Iron (27 mg) - folic acid (600 ug): Supplement serves as the Control (providing the current standard of care during pregnancy). Mothers instructed to take 1 tablet per day, from the 1st trimester through 12 weeks post-partum. | 2,912 | 13,333 | OG000 | ClinicalTrials.gov |
| Group 2 | Multiple Micronutrient | Multiple micronutrient: Containing 15 micronutrients all at an RDA including: vitamin A (770 ug retinol equivalents, vitamin D (5 ug), vitamin E (15 mg), folic acid (600 ug), thiamin (1.4 mg), riboflavin (1.4 mg), niacin (18 mg), vitamin B-12 (2.6 mg), vitamin B-6 (1.9 mg), vitamin C (85 mg), iron (27 mg), zinc (12 mg), iodine (220 ug), copper (1000 ug), selenium (60 ug).~Mothers instructed to take 1 tablet per day, from the 1st trimester through 12 weeks post-partum. | 2,510 | 13,475 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Preterm Birth | ClinicalTrials.gov |
| Description | Being born before 37 weeks of gestation | ClinicalTrials.gov |
| Time frame | Up to 37 weeks of gestation | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Antenatal Micronutrient Supplementation and Infant Survival | ClinicalTrials.gov |
| NCT number | NCT00860470 | ClinicalTrials.gov |
| Phases | PHASE3 | ClinicalTrials.gov |
| Conditions | Infant Mortality, Preterm Birth, Low Birth Weight, Neonatal Mortality, Perinatal Mortality | ClinicalTrials.gov |
| Interventions | Iron (27 mg) - folic acid (600 ug), Multiple micronutrient | ClinicalTrials.gov |
| Lead sponsor | Johns Hopkins Bloomberg School of Public Health | ClinicalTrials.gov |
| Results first posted | 2015-05-27 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT00860470?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.