Comparison · NCT00867048-48089c4c
Early ART vs Deferred ART: Transmission Risk Behavior Outcome 1
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Early ART vs Deferred ART: Transmission Risk Behavior Outcome 1. Trial comparisons, record NCT00867048-48089c4c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00867048-48089c4c
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.126 | 0.109 | 0.146 | wilson | |
| Risk in group 2 | 0.131 | 0.113 | 0.151 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00437 | -0.0311 | 0.0223 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.967 | 0.785 | 1.19 | log | |
| Odds ratio, group 1 over group 2 | 0.962 | 0.758 | 1.22 | log | |
| Number needed to treat, for one fewer participant with the outcome on Early ART than on Deferred ART | 229 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Early ART | Initiate ART immediately following randomization~All licensed antiretroviral medications: In both arms, participants may be prescribed any licensed antiretroviral medication, in accordance with national treatment guidelines. The nature of the intervention is the timing of when to begin treatment with these medications, as described in the two treatment arms.~ART dosage and frequency were based on clinical decision in accordance with local/national prescribing guidelines. | 156 | 1,236 | OG000 |
| Group 2 | Deferred ART | Defer ART until the CD4+ count declines to \<350 cells/cu mm or AIDS develops~All licensed antiretroviral medications: In both arms, participants may be prescribed any licensed antiretroviral medication, in accordance with national treatment guidelines. The nature of the intervention is the timing of when to begin treatment with these medications, as described in the two treatment arms.~ART dosage and frequency were based on clinical decision in accordance with local/national prescribing guidelines. | 155 | 1,187 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Transmission Risk Behavior Outcome 1
- Description
Proportion of participants identifying as men who have sex with men (MSM) engaging in condomless sex with HIV serodifferent partners (CLS-D) at study month 12. Participant completed a self-reported questionnaire on transmission risk behavior during the past two months at the month 12 visit following randomization.
- Time frame
- 12 months
- Population
Source ClinicalTrials.gov
Trial
- Title
- Strategic Timing of Antiretroviral Treatment
- NCT number
- NCT00867048
- Phases
- PHASE4
- Conditions
- HIV Infection
- Interventions
- All licensed antiretroviral medications
- Lead sponsor
- University of Minnesota
- Results first posted
- 2023-12-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00867048?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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