Comparison · NCT00910299-030a2a88
Prasugrel vs Clopidogrel: Number of Participants With Composite Endpoint of Cardiovascular Death or Myocardial Infarction (MI)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Prasugrel vs Clopidogrel: Number of Participants With Composite Endpoint of Cardiovascular Death or Myocardial Infarction (MI). Trial comparisons, record NCT00910299-030a2a88. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00910299-030a2a88
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0 | 0 | 0.0178 | wilson | |
| Risk in group 2 | 0.00474 | 0.000837 | 0.0264 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00474 | -0.0264 | 0.0135 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one fewer participant with the outcome on Prasugrel than on Clopidogrel | 211 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Prasugrel | One time 60 milligram (mg) oral loading dose and 10 mg once daily oral maintenance dose up to 6 months | 0 | 212 | OG000 |
| Group 2 | Clopidogrel | 75 mg oral daily maintenance dose up to 6 months. | 1 | 211 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants With Composite Endpoint of Cardiovascular Death or Myocardial Infarction (MI)
- Description
- The endpoint in this measure is a combination of cardiovascular death or MI.
- Time frame
- Baseline through 6 months
- Population
- Participants who were randomized.
Source ClinicalTrials.gov
Trial
- Title
- Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI)
- NCT number
- NCT00910299
- Phases
- PHASE2
- Conditions
- Coronary Artery Disease (CAD)
- Interventions
- Prasugrel, Clopidogrel
- Lead sponsor
- Eli Lilly and Company
- Results first posted
- 2012-06-08
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00910299?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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