Comparison · NCT00911508-ba85cc2e
Left Atrial Ablation vs Rate or Rhythm Control Therapy: Number of Participants Free From Recurrent Atrial Fibrillation (AF) Following the 90 Day Blanking Period
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Left Atrial Ablation vs Rate or Rhythm Control Therapy: Number of Participants Free From Recurrent Atrial Fibrillation (AF) Following the 90 Day Blanking Period. Trial comparisons, record NCT00911508-ba85cc2e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00911508-ba85cc2e
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.499 | 0.46 | 0.539 | wilson | |
| Risk in group 2 | 0.695 | 0.658 | 0.729 | wilson | |
| Risk difference, group 1 minus group 2 | -0.196 | -0.248 | -0.141 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.719 | 0.654 | 0.79 | log | |
| Odds ratio, group 1 over group 2 | 0.438 | 0.347 | 0.552 | log | |
| Number needed to treat, for one fewer participant with the outcome on Left Atrial Ablation than on Rate or Rhythm Control Therapy | 5.11 | 4.03 | 7.07 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Left Atrial Ablation | All patients randomized to the ablation group were required to undergo left atrial pulmonary vein isolation. The addition of ancillary ablation techniques including linear, ganglion plexus, and electrogram-based approaches were left to the discretion of the investigators. | 305 | 611 | OG000 |
| Group 2 | Rate or Rhythm Control Therapy | All patients randomized to drug therapy, were treated with standard rhythm and/or rate control drugs selected in accordance with contemporary guidelines, according to investigator discretion. | 437 | 629 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Free From Recurrent Atrial Fibrillation (AF) Following the 90 Day Blanking Period
- Description
Data from patients using the study provided ECG event recording system were analyzed. A 30-second episode of AF in either group, confirmed through blinded review by an ECG Core Lab Committee was used for defining the endpoint of recurrent AF.
- Time frame
- From date of therapy initiation until date of first AF recurrence following a 90 day wait (blanking) period over a median follow-up of 48.5 months.
- Population
- Subjects were analyzed in the post-blanking period if randomized treatment occurred and the subject did not die, withdraw, or get lost to follow-up before the end of the 90 day blanking period.
Source ClinicalTrials.gov
Trial
- Title
- Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial
- NCT number
- NCT00911508
- Phases
- NA
- Conditions
- Atrial Fibrillation, Arrhythmia
- Interventions
- Left atrial ablation, Rate or Rhythm Control Therapy
- Lead sponsor
- Mayo Clinic
- Results first posted
- 2019-08-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00911508?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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