Comparison · NCT00944710-83dea790
Intensified Treatment vs Control: Treatment Group Comparison of the Proportion of Participants Who Have Improved by 2 or More logMAR Visual Acuity Lines at 10 Weeks Since Randomization
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Intensified Treatment vs Control: Treatment Group Comparison of the Proportion of Participants Who Have Improved by 2 or More logMAR Visual Acuity Lines at 10 Weeks Since Randomization. Trial comparisons, record NCT00944710-83dea790. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00944710-83dea790
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.273 | 0.151 | 0.442 | wilson | |
| Risk in group 2 | 0.205 | 0.108 | 0.355 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0676 | -0.126 | 0.263 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.33 | 0.579 | 3.05 | log | |
| Odds ratio, group 1 over group 2 | 1.45 | 0.488 | 4.33 | log | |
| Number needed to treat, for one more participant with the outcome on Intensified Treatment than on Control | 14.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intensified Treatment | Weekend atropine 1% with plano lens over the sound eye~Atropine: Weekend atropine 1%~Plano lens: plano lens over the sound eye | 9 | 33 | OG001 |
| Group 2 | Control | Weekend atropine 1%~Atropine: Weekend atropine 1% | 8 | 39 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Treatment Group Comparison of the Proportion of Participants Who Have Improved by 2 or More logMAR Visual Acuity Lines at 10 Weeks Since Randomization
- Description
The proportion of participants who improved at least 2 logMAR lines since randomization was computed at the 10-week outcome.~The secondary outcome analysis was a treatment group comparison of the proportion of participants whose 10-week masked amblyopic eye visual acuity improved at least 2 logMAR lines since randomization using logistic regression, adjusting for visual acuity at randomization. The analysis included data from 10-week visual acuity exams completed between 8 to 15 weeks (inclusive) according to the principles specified in the primary outcome analysis.
- Time frame
- 10 weeks after randomization
- Population
- The analysis included data from 10-week visual acuity exams completed between 8 to 15 weeks (inclusive) according to the principles specified in the primary outcome analysis.
Source ClinicalTrials.gov
Trial
- Title
- Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
- NCT number
- NCT00944710
- Phases
- PHASE3
- Conditions
- Amblyopia
- Interventions
- Atropine, Plano lens, Atropine
- Lead sponsor
- Jaeb Center for Health Research
- Results first posted
- 2014-10-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00944710?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT00944710-83dea790