Comparison · NCT00965991-a2091075
Metformin vs Glyburide: Number of Participants Assessed for Glucose Control
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Metformin vs Glyburide: Number of Participants Assessed for Glucose Control. Trial comparisons, record NCT00965991-a2091075. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00965991-a2091075
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.667 | 0.554 | 0.763 | wilson | |
| Risk in group 2 | 0.676 | 0.563 | 0.771 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00901 | -0.157 | 0.139 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.987 | 0.788 | 1.24 | log | |
| Odds ratio, group 1 over group 2 | 0.96 | 0.485 | 1.9 | log | |
| Number needed to treat, for one fewer participant with the outcome on Metformin than on Glyburide | 111 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Metformin | metformin: patients received glyburide initial dose of 500 mg PO BID. Increased as necessary to a maximum dose of 2000 mg QD to control blood glucose | 50 | 75 | OG000 |
| Group 2 | Glyburide | Glyburide: Initial dose of 2.5mg PO BID increased as necessary to a maximum dose of 20 mg (10mg BID) QD to control blood glucose | 50 | 74 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants Assessed for Glucose Control
- Description
The importance of exercise in the management of blood glucose was emphasized, and 30 minutes of walking per day was recommended. Patients received instruction from a nurse educator or a certified diabetes educator regarding diet and the use of the glucometer. Number of participants with a glucose level \<100 mg/dL.
- Time frame
- fasting and 2 hour postprandial blood glucose
- Population
Source ClinicalTrials.gov
Trial
- Title
- Metformin Compared to Glyburide in Gestational Diabetes
- NCT number
- NCT00965991
- Phases
- NA
- Conditions
- Gestational Diabetes
- Interventions
- metformin, Glyburide
- Lead sponsor
- University of New Mexico
- Results first posted
- 2023-12-21
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00965991?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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