Comparison · NCT00986245-256d34d2
Once-daily of Ropinirole PR vs Twice-daily of Ropinirole PR: Patients Who Have Global Impression for Improvement to Severity of Motor Fluctuation
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Once-daily of Ropinirole PR vs Twice-daily of Ropinirole PR: Patients Who Have Global Impression for Improvement to Severity of Motor Fluctuation. Trial comparisons, record NCT00986245-256d34d2. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00986245-256d34d2
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.459 | 0.34 | 0.583 | wilson | |
| Risk in group 2 | 0.557 | 0.433 | 0.675 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0984 | -0.266 | 0.0771 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.824 | 0.579 | 1.17 | log | |
| Odds ratio, group 1 over group 2 | 0.674 | 0.33 | 1.38 | log | |
| Number needed to treat, for one fewer participant with the outcome on Once-daily of Ropinirole PR than on Twice-daily of Ropinirole PR | 10.2 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Once-daily of Ropinirole PR | Once-daily regimen of Ropinirole PR administered in either first intervention peirod or second intervention period. | 28 | 61 | OG000 |
| Group 2 | Twice-daily of Ropinirole PR | Twice-daily regimen of Ropinirole PR administered in either first intervention peirod or second intervention period. | 34 | 61 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Patients Who Have Global Impression for Improvement to Severity of Motor Fluctuation
- Description
- Patients who have global impression for improvement to severity of motor fluctuation compared
- Time frame
- After 8 weeks in each arm or at last visit for early completion
- Population
- The number of patient who completed the study and answered the questionnaire for global impression to motor fluctuation severity.
Source ClinicalTrials.gov
Trial
- Title
- Study to Compare the Effect of Ropinirole Prolonged Release Once-daily Versus Twice-daily
- NCT number
- NCT00986245
- Phases
- PHASE4
- Conditions
- Parkinson Disease
- Interventions
- Ropinirole Prolonged release
- Lead sponsor
- Seoul National University Hospital
- Results first posted
- 2013-09-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00986245?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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