Comparison · NCT00991029-e1e885cf
Clopidogrel vs Placebo: Composite of Ischemic Stroke, Myocardial Infarction, Death From Ischemic Vascular Causes, or Major Hemorrhage
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Clopidogrel vs Placebo: Composite of Ischemic Stroke, Myocardial Infarction, Death From Ischemic Vascular Causes, or Major Hemorrhage. Trial comparisons, record NCT00991029-e1e885cf. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00991029-e1e885cf
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.058 | 0.0494 | 0.068 | wilson | |
| Risk in group 2 | 0.0682 | 0.0589 | 0.0789 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0102 | -0.0239 | 0.00346 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.85 | 0.684 | 1.06 | log | |
| Odds ratio, group 1 over group 2 | 0.841 | 0.667 | 1.06 | log | |
| Number needed to treat, for one fewer participant with the outcome on Clopidogrel than on Placebo | 97.9 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Clopidogrel | Patients assigned to clopidogrel in addition to aspirin~Clopidogrel: Loading dose of 600mg followed by 75 milligrams, oral, one tablet daily for 89 days | 141 | 2,432 | OG000 |
| Group 2 | Placebo | Patients assigned to placebo in addition to aspirin~placebo: Loading dose of 8 tablets followed by one tablet daily for 89 days | 167 | 2,449 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Composite of Ischemic Stroke, Myocardial Infarction, Death From Ischemic Vascular Causes, or Major Hemorrhage
- Description
- Secondary efficacy outcome: Number of participants with ischemic stroke, myocardial infarction, death from ischemic vascular causes, or major hemorrhage
- Time frame
- Up to 90 days
- Population
Source ClinicalTrials.gov
Trial
- Title
- Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
- NCT number
- NCT00991029
- Phases
- PHASE3
- Conditions
- Ischemic Attack, Transient
- Interventions
- Clopidogrel, placebo
- Lead sponsor
- University of California, San Francisco
- Results first posted
- 2018-12-04
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00991029?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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