Comparison · NCT01007448-sae
Bexarotene 150 mg/m^2/Day vs Bexarotene 300 mg/m^2/Day: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Bexarotene 150 mg/m^2/Day vs Bexarotene 300 mg/m^2/Day: serious adverse events. Trial comparisons, record NCT01007448-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01007448-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.367 | 0.219 | 0.545 | wilson | |
| Risk in group 2 | 0.448 | 0.284 | 0.625 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0816 | -0.312 | 0.161 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.818 | 0.44 | 1.52 | log | |
| Odds ratio, group 1 over group 2 | 0.713 | 0.251 | 2.02 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Bexarotene 150 mg/m^2/Day than on Bexarotene 300 mg/m^2/Day | 12.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Bexarotene 150 mg/m^2/Day | Participants received bexarotene 150 mg/m\^2/day once daily for 24 weeks. | 11 | 30 | EG000 |
| Group 2 | Bexarotene 300 mg/m^2/Day | Participants received bexarotene 300 mg/m\^2/day once daily for 24 weeks. | 13 | 29 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Baseline up to Week 28
Source ClinicalTrials.gov
Trial
- Title
- Study Evaluating Two Dose Levels of Targretin Capsules in Participants With Refractory Cutaneous T-Cell Lymphoma (CTCL)
- NCT number
- NCT01007448
- Phases
- PHASE4
- Conditions
- Refractory Cutaneous T-cell Lymphoma
- Interventions
- Bexarotene
- Lead sponsor
- Bausch Health Americas, Inc.
- Results first posted
- 2019-11-12
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01007448?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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