Comparison · NCT01029782-cb7ce747
IV Cefazolin Plus Oral Probenecid and Placebo Cephalexin vs Oral Cephalexin and Saline IV Plus Probenecid Placebo: The Number of Patients Failing Therapy After 72 Hours of Antibiotic Treatment With Oral Cephalexin or Intravenous Cefazolin Plus Oral Probenecid.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. IV Cefazolin Plus Oral Probenecid and Placebo Cephalexin vs Oral Cephalexin and Saline IV Plus Probenecid Placebo: The Number of Patients Failing Therapy After 72 Hours of Antibiotic Treatment With Oral Cephalexin or Intravenous Cefazolin Plus Oral Probenecid. Trial comparisons, record NCT01029782-cb7ce747. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01029782-cb7ce747
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0606 | 0.0281 | 0.126 | wilson | |
| Risk in group 2 | 0.0417 | 0.0163 | 0.102 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0189 | -0.0499 | 0.089 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.45 | 0.424 | 4.99 | log | |
| Odds ratio, group 1 over group 2 | 1.48 | 0.405 | 5.43 | log | |
| Number needed to treat, for one more participant with the outcome on IV Cefazolin Plus Oral Probenecid and Placebo Cephalexin than on Oral Cephalexin and Saline IV Plus Probenecid Placebo | 52.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | IV Cefazolin Plus Oral Probenecid and Placebo Cephalexin | IV cefazolin plus oral probenecid and placebo cephalexin: Intravenous cefazolin 2 g IV plus probenecid 1 g daily plus cephalexin placebo orally four times daily. | 6 | 99 | OG000 |
| Group 2 | Oral Cephalexin and Saline IV Plus Probenecid Placebo | Oral cephalexin and saline IV plus probenecid placebo: Cephalexin 500 mg orally four times daily plus saline IV and oral probenecid placebo daily | 4 | 96 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- The Number of Patients Failing Therapy After 72 Hours of Antibiotic Treatment With Oral Cephalexin or Intravenous Cefazolin Plus Oral Probenecid.
- Description
- Time frame
- 72 hours
- Population
- Per-Protocol Analysis at 72 hours.
Source ClinicalTrials.gov
Trial
- Title
- Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis
- NCT number
- NCT01029782
- Phases
- PHASE2
- Conditions
- Cellulitis
- Interventions
- IV cefazolin plus oral probenecid and placebo cephalexin, Oral cephalexin and saline IV plus probenecid placebo
- Lead sponsor
- Kelowna General Hospital
- Results first posted
- 2018-08-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01029782?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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