Comparison · NCT01051323-sae
Methoxy Polyethylene Glycol-epoetin Beta (Predialysis) vs Methoxy Polyethylene Glycol-epoetin Beta (Hemodialysis): serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Methoxy Polyethylene Glycol-epoetin Beta (Predialysis) vs Methoxy Polyethylene Glycol-epoetin Beta (Hemodialysis): serious adverse events. Trial comparisons, record NCT01051323-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01051323-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0202 | 0.00983 | 0.0412 | wilson | |
| Risk in group 2 | 0.0558 | 0.0442 | 0.0702 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0356 | -0.0534 | -0.0116 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.363 | 0.168 | 0.783 | log | |
| Odds ratio, group 1 over group 2 | 0.349 | 0.159 | 0.768 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Methoxy Polyethylene Glycol-epoetin Beta (Predialysis) than on Methoxy Polyethylene Glycol-epoetin Beta (Hemodialysis) | 28.1 | 18.7 | 86.1 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Methoxy Polyethylene Glycol-epoetin Beta (Predialysis) | Participants received methoxy polyethylene glycol-epoetin beta intravenously or subcutaneously as prescribed by the physician and were observed for 12 months. The actual dose was chosen by the physician and was adjusted as necessary. | 7 | 346 | EG000 |
| Group 2 | Methoxy Polyethylene Glycol-epoetin Beta (Hemodialysis) | Participants received methoxy polyethylene glycol-epoetin beta intravenously or subcutaneously as prescribed by the physician and were observed for 12 months. The actual dose was chosen by the physician and was adjusted as necessary. | 67 | 1,201 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Month 0 to Month 12
Source ClinicalTrials.gov
Trial
- Title
- An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Renal Anemia
- NCT number
- NCT01051323
- Phases
- Conditions
- Anemia
- Interventions
- methoxy polyethylene glycol-ep [Mircera]
- Lead sponsor
- Hoffmann-La Roche
- Results first posted
- 2015-12-18
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01051323?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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