Comparison · NCT01072500-7e77f48a
Physical Activity vs Successful Aging: Major Mobility Disability, Defined as Incapacity to Walk 400 Meters
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Physical Activity vs Successful Aging: Major Mobility Disability, Defined as Incapacity to Walk 400 Meters. Trial comparisons, record NCT01072500-7e77f48a. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01072500-7e77f48a
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.301 | 0.27 | 0.333 | wilson | |
| Risk in group 2 | 0.355 | 0.323 | 0.388 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0542 | -0.0994 | -0.00871 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.847 | 0.737 | 0.974 | log | |
| Odds ratio, group 1 over group 2 | 0.782 | 0.635 | 0.961 | log | |
| Number needed to treat, for one fewer participant with the outcome on Physical Activity than on Successful Aging | 18.4 | 10.1 | 115 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Physical Activity | The physical activity intervention consists primarily of walking at moderate intensity, lower extremity resistance exercises, balance exercises, stretching and behavioral counseling. | 246 | 818 | OG000 |
| Group 2 | Successful Aging | The successful aging intervention consists of health education seminars regarding health-related matters and upper extremity stretching exercises. | 290 | 817 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Major Mobility Disability, Defined as Incapacity to Walk 400 Meters
- Description
The primary outcome of major mobility disability was defined as the inability to complete a 400-m walk test within 15 minutes without sitting and without the help of another person or walker. Use of a cane was acceptable. Participants were asked to walk 400 m at their usual pace, without overexerting, on a 20 meter course for 10 laps (40 meters/lap). Participants were allowed to stop for up to 1 minute for fatigue or related symptoms. When major mobility disability could not be objectively measured because of the inability of the participant to come to the clinic and absence of a suitable walking course at the participant's home, institution, or hospital, an alternative adjudication of the outcome was based on objective inability to walk 4 meters in less than 10 seconds, or self-, proxy-, or medical record-reported inability to walk across a room. If participants met these alternative criteria, they would not be able to complete the 400 meter walk within 15 minutes.
- Time frame
- Median 2.7 years/Average 2.6 years
- Population
Source ClinicalTrials.gov
Trial
- Title
- The LIFE Study - Lifestyle Interventions and Independence for Elders
- NCT number
- NCT01072500
- Phases
- PHASE3
- Conditions
- Sedentary Lifestyle, Risk of Disability, Aging
- Interventions
- Physical Activity, Successful Aging
- Lead sponsor
- University of Florida
- Results first posted
- 2016-04-18
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01072500?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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