Comparison · NCT01095731-deaths
Tiopronin, Hunt Hess Grade I-V vs Sugar Pill, Hunt Hess Grade I-V: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Tiopronin, Hunt Hess Grade I-V vs Sugar Pill, Hunt Hess Grade I-V: deaths from any cause. Trial comparisons, record NCT01095731-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01095731-deaths
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.138 | 0.055 | 0.306 | wilson | |
| Risk in group 2 | 0.111 | 0.0385 | 0.281 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0268 | -0.162 | 0.21 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.24 | 0.305 | 5.05 | log | |
| Odds ratio, group 1 over group 2 | 1.28 | 0.259 | 6.33 | log | |
| Number needed to harm, for one more death from any cause on Tiopronin, Hunt Hess Grade I-V than on Sugar Pill, Hunt Hess Grade I-V | 37.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Tiopronin, Hunt Hess Grade I-V | Good Grade (Hunt Hess I-III) and Poor Grade (Hunt Hess IV-V)~Tiopronin: Dosage will be 1 gram, 3 times daily. Drug dosing will be initiated at time of aSAH confirmation, for a length of 14 days or at hospital discharge. | 4 | 29 | EG000 |
| Group 2 | Sugar Pill, Hunt Hess Grade I-V | Good Grade (Hunt Hess I-III) and Poor Grade (Hunt Hess IV-V)~Placebo: Dosage will be 1 gram, 3 times daily. Drug dosing will be initiated at time of aSAH confirmation, for a length of 14 days or at hospital discharge. | 3 | 27 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage
- NCT number
- NCT01095731
- Phases
- PHASE2
- Conditions
- Aneurysmal Subarachnoid Hemorrhage
- Interventions
- Tiopronin, Placebo
- Lead sponsor
- E. Sander Connolly
- Results first posted
- 2025-10-29
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01095731?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT01095731-deaths