Comparison · NCT01139658-56b79376
Total Knee Replacement vs Total Hip Replacement: Number of Patients Who Switched to Another Anticoagulant Therapy
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Total Knee Replacement vs Total Hip Replacement: Number of Patients Who Switched to Another Anticoagulant Therapy. Trial comparisons, record NCT01139658-56b79376. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01139658-56b79376
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0576 | 0.0431 | 0.0767 | wilson | |
| Risk in group 2 | 0.0484 | 0.0364 | 0.0642 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0092 | -0.0123 | 0.0318 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.19 | 0.792 | 1.79 | log | |
| Odds ratio, group 1 over group 2 | 1.2 | 0.782 | 1.85 | log | |
| Number needed to treat, for one more participant with the outcome on Total Knee Replacement than on Total Hip Replacement | 109 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Total Knee Replacement | Patients undergoing elective total knee replacement (TKR) received a dose of dabigatran etexilate; the administered treatment was based on usual practice in a real-life setting. | 43 | 746 | OG000 |
| Group 2 | Total Hip Replacement | Patients undergoing elective total hip replacement (THR) received a dose of dabigatran etexilate; the administered treatment was based on usual practice in a real-life setting. | 45 | 929 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Patients Who Switched to Another Anticoagulant Therapy
- Description
- Treated population included patients who took at least one dose of Pradaxa. One additional patient was excluded from the analysis as they were missing their date of first dose.
- Time frame
- 11 weeks
- Population
Source ClinicalTrials.gov
Trial
- Title
- Prevention of Venous Thromboembolic Events After Elective Orthopaedic Surgery in Patients Treated With PRADAXA
- NCT number
- NCT01139658
- Phases
- Conditions
- Venous Thromboembolism
- Interventions
- Lead sponsor
- Boehringer Ingelheim
- Results first posted
- 2014-01-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01139658?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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