Comparison · NCT01195636-sae
XPF-002 vs Placebo: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. XPF-002 vs Placebo: serious adverse events. Trial comparisons, record NCT01195636-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01195636-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0161 | 0.00285 | 0.0859 | wilson | |
| Risk in group 2 | 0.0159 | 0.00281 | 0.0846 | wilson | |
| Risk difference, group 1 minus group 2 | 0.000256 | -0.0697 | 0.0712 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.02 | 0.065 | 15.9 | log | |
| Odds ratio, group 1 over group 2 | 1.02 | 0.0622 | 16.6 | log | |
| Number needed to harm, for one more participant with a serious adverse event on XPF-002 than on Placebo | 3,910 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | XPF-002 | XPF-002: 8% strength ointment, applied twice daily for 3 weeks in either the first intervention period or second intervention period. | 1 | 62 | EG000 |
| Group 2 | Placebo | Placebo: Vehicle only ointment, applied twice daily for 3 weeks in either first intervention period or second intervention period. | 1 | 63 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)
- NCT number
- NCT01195636
- Phases
- PHASE2
- Conditions
- Postherpetic Neuralgia
- Interventions
- XPF-002, Placebo
- Lead sponsor
- Xenon Pharmaceuticals Inc.
- Results first posted
- 2013-11-25
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01195636?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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