Comparison · NCT01197417-sae
Magnesium Group vs Placebo Group: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Magnesium Group vs Placebo Group: serious adverse events. Trial comparisons, record NCT01197417-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01197417-sae
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.129 | 0.0768 | 0.208 | wilson | |
| Risk in group 2 | 0.117 | 0.0679 | 0.193 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0122 | -0.08 | 0.105 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.1 | 0.53 | 2.3 | log | |
| Odds ratio, group 1 over group 2 | 1.12 | 0.485 | 2.59 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Magnesium Group than on Placebo Group | 81.9 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Magnesium Group | Intravenous Magnesium Sulfate Intravenous Magnesium Sulfate: 40 mg/kg (max 2.4 grams), infused at a concentration of 40 mg/ml (1 ml/kg, max 60 ml), every 8 hours for a total of 6 doses | 13 | 101 | EG000 |
| Group 2 | Placebo Group | Normal Saline placebo Normal Saline Placebo: (1 ml/kg, max 60 ml), administered every 8 hours for a total of 6 doses | 12 | 103 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis
- NCT number
- NCT01197417
- Phases
- PHASE2, PHASE3
- Conditions
- Sickle Cell Disease
- Interventions
- Intravenous Magnesium Sulfate, Normal Saline Placebo
- Lead sponsor
- Medical College of Wisconsin
- Results first posted
- 2015-09-07
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01197417?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT01197417-sae