Comparison · NCT01287221-sae
Rifampicin vs Placebo: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Rifampicin vs Placebo: serious adverse events. Trial comparisons, record NCT01287221-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01287221-sae
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.06 | 0.0206 | 0.162 | wilson | |
| Risk in group 2 | 0.24 | 0.143 | 0.374 | wilson | |
| Risk difference, group 1 minus group 2 | -0.18 | -0.32 | -0.0391 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.25 | 0.0751 | 0.832 | log | |
| Odds ratio, group 1 over group 2 | 0.202 | 0.0532 | 0.768 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Rifampicin than on Placebo | 5.56 | 3.13 | 25.6 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Rifampicin | Subjects randomized to this arm will receive 300 mg Rifampicin two times a day for 12 months. | 3 | 50 | EG000 |
| Group 2 | Placebo | Subjects randomized to this arm will receive placebo capsules twice daily for 12 months. The capsules will contain riboflavin (vitamin B2). | 12 | 50 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Adverse events were to be recorded from the time a participant signed the informed consent form and throughout the 12 months of the study, even if they prematurely discontinued the study drug.
Source ClinicalTrials.gov
Trial
- Title
- Study of Rifampicin in Multiple System Atrophy
- NCT number
- NCT01287221
- Phases
- PHASE3
- Conditions
- Multiple System Atrophy
- Interventions
- Rifampicin, placebo
- Lead sponsor
- Phillip Low
- Results first posted
- 2014-03-28
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01287221?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT01287221-sae