Comparison · NCT01308749-0ce29bf5
Sequence 2: Placebo:Oxytocin vs Sequence 1: Oxytocin:Oxytocin: Number of Participants Who Could Tolerate Twice Daily Oxytocin
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Sequence 2: Placebo:Oxytocin vs Sequence 1: Oxytocin:Oxytocin: Number of Participants Who Could Tolerate Twice Daily Oxytocin. Trial comparisons, record NCT01308749-0ce29bf5. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01308749-0ce29bf5
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 1 | 0.772 | 1 | wilson | |
| Risk in group 2 | 0.917 | 0.646 | 0.985 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0833 | -0.155 | 0.354 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.09 | 0.92 | 1.29 | log | |
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one more participant with the outcome on Sequence 2: Placebo:Oxytocin than on Sequence 1: Oxytocin:Oxytocin | 12 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Sequence 2: Placebo:Oxytocin | Intervention: Drug: placebo double blind for 8 weeks then oxytocin open label for 8 weeks | 13 | 13 | OG000 |
| Group 2 | Sequence 1: Oxytocin:Oxytocin | Intervention: Drug: oxytocin = Syntocinon® Nasal Spray~total of 16 weeks exposure Subjects ages 3-10 years old will be titrated up to a maximum dose of 24IU. Subjects ages 11-17 years old will be titrated up to a maximum dose of 32IU. | 11 | 12 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants Who Could Tolerate Twice Daily Oxytocin
- Description
This study will help to determine tolerability of intranasal oxytocin treatment in children with autism by measuring the ability of at least 80% of the sample to tolerate twice daily intranasal administration of oxytocin.
- Time frame
- Week 0 to week 8
- Population
- This is over period 1, the double blind phase (week 0 to week 8) only
Source ClinicalTrials.gov
Trial
- Title
- A Study of Oxytocin in Children and Adolescents With Autistic Disorder
- NCT number
- NCT01308749
- Phases
- PHASE2
- Conditions
- Autism
- Interventions
- Oxytocin, Placebo
- Lead sponsor
- University of North Carolina, Chapel Hill
- Results first posted
- 2017-07-17
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01308749?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT01308749-0ce29bf5