Home Assessment and Initiation of ART vs Clinic-based ART Assessment and Initiation: ART Initiation

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measures 6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measure	Value	95% interval, lower	95% interval, upper	Method	Source
Risk in group 1	0.0221	0.0191	0.0255	wilson	ClinicalTrials.gov
Risk in group 2	0.00744	0.00582	0.00951	wilson	ClinicalTrials.gov
Risk difference, group 1 minus group 2	0.0146	0.011	0.0184	newcombe hybrid score	ClinicalTrials.gov
Risk ratio, group 1 over group 2	2.97	2.23	3.95	log	ClinicalTrials.gov
Odds ratio, group 1 over group 2	3.01	2.26	4.02	log	ClinicalTrials.gov
Number needed to treat, for one more participant with the outcome on Home Assessment and Initiation of ART than on Clinic-based ART Assessment and Initiation	68.3	54.3	90.6	from the risk difference interval	ClinicalTrials.gov

Groups 2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

Group	Title	Description	With the outcome	Analysed	ClinicalTrials.gov code	Source
Group 1	Home Assessment and Initiation of ART	Optional home initiation of HIV care following HIV self-testing	181	8,194	OG000	ClinicalTrials.gov
Group 2	Clinic-based ART Assessment and Initiation	Facility-based HIV care following HIV self-testing only	63	8,466	OG001	ClinicalTrials.gov

Outcome 5

Field	Value	Source
Type	PRIMARY	ClinicalTrials.gov
Title	ART Initiation	ClinicalTrials.gov
Description	Comparison between study arms of the proportion of all resident adults (per capita, and irrespective of HIV status or participation in home-based HIV testing intervention) who initiate ART during the first 6 months of the home-based HIV-testing intervention.	ClinicalTrials.gov
Time frame	First six months following introduction of home-based HIV testing	ClinicalTrials.gov
Population		ClinicalTrials.gov

Trial 8

Field	Value	Source
Title	Home Assessment and Initiation of Antiretroviral Therapy for HIV in Malawi	ClinicalTrials.gov
NCT number	NCT01414413	ClinicalTrials.gov
Phases	NA	ClinicalTrials.gov
Conditions	HIV	ClinicalTrials.gov
Interventions	Home assessment and initiation of ART, Clinic-based ART assessment and initiation	ClinicalTrials.gov
Lead sponsor	Liverpool School of Tropical Medicine	ClinicalTrials.gov
Results first posted	2014-04-07	ClinicalTrials.gov
Results on ClinicalTrials.gov	https://clinicaltrials.gov/study/NCT01414413?tab=results	ClinicalTrials.gov

Source 4

Field	Value	Source
Release	trial-comparisons-2026-03-23-0.1.0	ClinicalTrials.gov
Release manifest SHA-256	f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57	ClinicalTrials.gov
AACT copy	2026-03-23	ClinicalTrials.gov
Tables read	outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet	ClinicalTrials.gov

The same record as JSON

Release trial-comparisons-2026-03-23-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.