Comparison · NCT01442038-sae
Ranolazine vs Placebo: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Ranolazine vs Placebo: serious adverse events. Trial comparisons, record NCT01442038-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01442038-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.39 | 0.364 | 0.417 | wilson | |
| Risk in group 2 | 0.374 | 0.348 | 0.401 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0164 | -0.0208 | 0.0535 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.04 | 0.947 | 1.15 | log | |
| Odds ratio, group 1 over group 2 | 1.07 | 0.915 | 1.25 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Ranolazine than on Placebo | 61.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ranolazine | Ranolazine 500 mg (1 x 500 mg tablet) twice daily for 7 days, followed by ranolazine 1000 mg (2 x 500 mg tablet) twice daily for the duration of the study (participants receiving a moderate CYP3A4 inhibitor continued to receive ranolazine 500 mg (1 x 500 mg tablet) twice daily for the duration of the study) | 516 | 1,322 | EG000 |
| Group 2 | Placebo | Ranolazine placebo (1 tablet) twice daily for 7 days, followed by ranolazine placebo (2 tablets) twice daily for the duration of the study (participants receiving a moderate CYP3A4 inhibitor continued to receive ranolazine placebo (1 tablet) twice daily for the duration of the study) | 485 | 1,297 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Baseline through end of study drug treatment (average exposure 72 weeks) plus 30 days
Source ClinicalTrials.gov
Trial
- Title
- Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)
- NCT number
- NCT01442038
- Phases
- PHASE3
- Conditions
- Coronary Artery Disease, Angina Pectoris
- Interventions
- Ranolazine, Placebo
- Lead sponsor
- Gilead Sciences
- Results first posted
- 2016-07-15
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01442038?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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