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Comparison · NCT01468909-deaths

Paclitaxel + Placebo vs Paclitaxel + Pazopanib: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Paclitaxel + Placebo vs Paclitaxel + Pazopanib: deaths from any cause. Trial comparisons, record NCT01468909-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01468909-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.40.2760.538wilson
Risk in group 20.4420.3160.577wilson
Risk difference, group 1 minus group 2-0.0423-0.2250.145newcombe hybrid score
Risk ratio, group 1 over group 20.9040.5731.43log
Odds ratio, group 1 over group 20.8410.3831.85log
Number needed to treat, for one fewer death from any cause on Paclitaxel + Placebo than on Paclitaxel + Pazopanib23.6from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Paclitaxel + PlaceboPaclitaxel 80 mg/m2 administered weekly on days 1, 8 and 15 with Placebo PO daily2050EG000
Group 2Paclitaxel + PazopanibPaclitaxel 80 mg/m2 administered weekly on days 1, 8 and 15 with Pazopanib 800 mg PO daily2352EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Every 28 days (1cycle) while on study treatment. Up to 30 days after treatment ends, up to 5 years.

Source ClinicalTrials.gov

Trial

Title
Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Persistent or Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
NCT number
NCT01468909
Phases
PHASE2
Conditions
Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma
Interventions
Laboratory Biomarker Analysis, Paclitaxel, Pazopanib Hydrochloride, Placebo
Lead sponsor
National Cancer Institute (NCI)
Results first posted
2019-04-16

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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