Comparison · NCT01472549-2ddaa8d4
Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Allergic Reaction
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Chlorhexidine-alcohol vs Iodine-alcohol: Number of Participants With Allergic Reaction. Trial comparisons, record NCT01472549-2ddaa8d4. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01472549-2ddaa8d4
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0035 | 0.000959 | 0.0127 | wilson | |
| Risk in group 2 | 0.00174 | 0.000307 | 0.00978 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00176 | -0.00668 | 0.011 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.01 | 0.183 | 22.1 | log | |
| Odds ratio, group 1 over group 2 | 2.01 | 0.182 | 22.3 | log | |
| Number needed to treat, for one more participant with the outcome on Chlorhexidine-alcohol than on Iodine-alcohol | 569 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Chlorhexidine-alcohol | 2% chlorhexidine gluconate with 70% alcohol (ChloraPrep, Cardinal Health)~Chlorhexidine-alcohol: Skin preparation with 2% chlorhexidine gluconate with 70% alcohol (ChloraPrep, Cardinal Health) preoperative skin preparation | 2 | 572 | OG000 |
| Group 2 | Iodine-alcohol | 8.3% povidone-iodine with 72.5% alcohol (Prevail-FX, Cardinal Health)~Iodine-alcohol: Skin preparation with 8.3% povidone-iodine with 72.5% alcohol (Prevail-FX, Cardinal Health) preoperative skin preparation. | 1 | 575 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Allergic Reaction
- Description
- Time frame
- 30 days
- Population
Source ClinicalTrials.gov
Trial
- Title
- The Skin Prep Study
- NCT number
- NCT01472549
- Phases
- NA
- Conditions
- Surgical Site Infections
- Interventions
- Iodine-alcohol, Chlorhexidine-alcohol
- Lead sponsor
- Washington University School of Medicine
- Results first posted
- 2018-08-08
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01472549?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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