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Comparison · NCT01478256-08ea2e8b

Besifloxocin vs Erythromycin: Improvement in Signs and Symptoms of Blepharitis

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Besifloxocin vs Erythromycin: Improvement in Signs and Symptoms of Blepharitis. Trial comparisons, record NCT01478256-08ea2e8b. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01478256-08ea2e8b

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 110.7961wilson
Risk in group 210.7961wilson
Risk difference, group 1 minus group 20-0.2040.204newcombe hybrid score
Risk ratio, group 1 over group 2111log
Odds ratio, group 1 over group 2loga cell of the two-by-two table is zero
Number needed to treatfrom the risk difference intervalthe two groups' risks are equal

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1BesifloxocinUse of topical besifloxocin to treat acute blepharitis1515OG000
Group 2ErythromycinTopical Erythromycin ointment for treatment of acute blepharitis1515OG001

Outcome

Type
PRIMARY
Title
Improvement in Signs and Symptoms of Blepharitis
Description
Signs and symptoms of blepharitis were scored and determined before and after treatment with two different antibiotics
Time frame
Four weeks
Population

Source ClinicalTrials.gov

Trial

Title
Comparative Study in the Efficacy of Topical Besifloxocin With Erythromycin for the Management of Acute Blepharitis
NCT number
NCT01478256
Phases
PHASE4
Conditions
Blepharitis
Interventions
Erythromycin, Besifloxocin
Lead sponsor
John, George, M.D.
Results first posted
2013-11-20

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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