MCI/OSA/CPAP Adherent vs MCI/OSA/CPAP Non-adherent: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.172 | 0.076 | 0.345 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0 | 0.0000000000000000139 | 0.133 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.172 | 0.00798 | 0.345 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | ClinicalTrials.gov | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | ClinicalTrials.gov | |||
| Number needed to harm, for one more participant with a serious adverse event on MCI/OSA/CPAP Adherent than on MCI/OSA/CPAP Non-adherent | 5.8 | 2.89 | 125 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | MCI/OSA/CPAP Adherent | Device: CPAP. Included those diagnosed with MCI and OSA. The diagnostic criteria for OSA was defined as an AHI score of greater than or equal to 10. CPAP was prescribed for nightly use. Mean CPAP use equal to or greater than 4 hours per night over one year. | 5 | 29 | EG000 | ClinicalTrials.gov |
| Group 2 | MCI/OSA/CPAP Non-adherent | Device: CPAP. Included those diagnosed with MCI and OSA. The diagnostic criteria for OSA was defined as an AHI score of greater than or equal to 10. CPAP was prescribed for nightly use. Mean CPAP use less than 4 hours per night over one year. | 0 | 25 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | 1 year | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Mild Cognitive Impairment and Obstructive Sleep Apnea | ClinicalTrials.gov |
| NCT number | NCT01482351 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Obstructive Sleep Apnea, Mild Cognitive Impairment | ClinicalTrials.gov |
| Interventions | CPAP adherence intervention, Attention control intervention | ClinicalTrials.gov |
| Lead sponsor | George Mason University | ClinicalTrials.gov |
| Results first posted | 2019-01-29 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT01482351?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.