Comparison · NCT01488448-1e12e780
Nebulized Hypertonic Saline vs Nebulized Normal Saline: Readmission for Bronchiolitis Within 7 Days of Discharge
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Nebulized Hypertonic Saline vs Nebulized Normal Saline: Readmission for Bronchiolitis Within 7 Days of Discharge. Trial comparisons, record NCT01488448-1e12e780. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01488448-1e12e780
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.043 | 0.0169 | 0.105 | wilson | |
| Risk in group 2 | 0.0309 | 0.0106 | 0.087 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0121 | -0.0498 | 0.0777 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.39 | 0.32 | 6.05 | log | |
| Odds ratio, group 1 over group 2 | 1.41 | 0.307 | 6.47 | log | |
| Number needed to treat, for one more participant with the outcome on Nebulized Hypertonic Saline than on Nebulized Normal Saline | 82.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Nebulized Hypertonic Saline | 4mL nebulized 3% sodium chloride every 4 hours until discharge~3% sodium chloride: 4 milliliters delivered via nebulizer with 5 Liters O2 flow every 4 hours until discharge | 4 | 93 | OG000 |
| Group 2 | Nebulized Normal Saline | 4 mL nebulized 0.9% sodium chloride every 4 hours until discharge~0.9% sodium chloride: 4 milliliters delivered via nebulizer with 5 Liters O2 flow every 4 hours until discharge | 3 | 97 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Readmission for Bronchiolitis Within 7 Days of Discharge
- Description
- Phone call at 7 days to assess for readmission to any hospital
- Time frame
- within 7 days of hospital discharge
- Population
- This population is those who completed the study.
Source ClinicalTrials.gov
Trial
- Title
- A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis
- NCT number
- NCT01488448
- Phases
- NA
- Conditions
- Bronchiolitis
- Interventions
- 3% sodium chloride, 0.9% sodium chloride
- Lead sponsor
- Montefiore Medical Center
- Results first posted
- 2014-08-22
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01488448?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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