With Concomitant Drugs vs Without Concomitant Drugs: Risk Factors for the Proportion of Responders of Tolterodine-Concomitant Drugs
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.827 | 0.815 | 0.838 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.856 | 0.844 | 0.867 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0296 | -0.0458 | -0.0133 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.965 | 0.947 | 0.984 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.801 | 0.708 | 0.905 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with the outcome on With Concomitant Drugs than on Without Concomitant Drugs | 33.8 | 21.8 | 75.1 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | With Concomitant Drugs | Participants with concomitant drugs who took tolterodine according to Japanese Package Insert. | 3,483 | 4,214 | OG000 | ClinicalTrials.gov |
| Group 2 | Without Concomitant Drugs | Participants without concomitant drugs who took tolterodine according to Japanese Package Insert. | 3,053 | 3,566 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Risk Factors for the Proportion of Responders of Tolterodine-Concomitant Drugs | ClinicalTrials.gov |
| Description | Number of participants with responders of tolterodine to determine whether with or without concomitant drugs is significant risk factor. | ClinicalTrials.gov |
| Time frame | 12 week | ClinicalTrials.gov |
| Population | The efficacy analysis population consists of the evaluable cases in accordance with the analysis plan (cases judged to have been evaluated appropriately). | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Tolterodine Drug Use Investigation.(Post Marketing Commitment Plan) | ClinicalTrials.gov |
| NCT number | NCT01488578 | ClinicalTrials.gov |
| Phases | ClinicalTrials.gov | |
| Conditions | Overactive Bladder | ClinicalTrials.gov |
| Interventions | Tolterodine tartrate | ClinicalTrials.gov |
| Lead sponsor | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | ClinicalTrials.gov |
| Results first posted | 2012-06-14 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT01488578?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.