Comparison · NCT01499511-10524dbf
ASCOT Participants Amlodipine vs ASCOT Participants Atenolol: Number of Participants Who Have Required Renal Replacement Therapy (Dialysis or Kidney Transplant) Since the End of the ASCOT Trial
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. ASCOT Participants Amlodipine vs ASCOT Participants Atenolol: Number of Participants Who Have Required Renal Replacement Therapy (Dialysis or Kidney Transplant) Since the End of the ASCOT Trial. Trial comparisons, record NCT01499511-10524dbf. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01499511-10524dbf
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0114 | 0.00623 | 0.0209 | wilson | |
| Risk in group 2 | 0.0109 | 0.00574 | 0.0206 | wilson | |
| Risk difference, group 1 minus group 2 | 0.000546 | -0.0105 | 0.0113 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.05 | 0.429 | 2.57 | log | |
| Odds ratio, group 1 over group 2 | 1.05 | 0.425 | 2.6 | log | |
| Number needed to treat, for one more participant with the outcome on ASCOT Participants Amlodipine than on ASCOT Participants Atenolol | 1,830 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | ASCOT Participants Amlodipine | It is follow up group from the ASCOT study, after treatment with amlodipine for 5.5 years. No treatment only follow up. | 10 | 874 | OG000 |
| Group 2 | ASCOT Participants Atenolol | It is follow up group from the ASCOT study, after treatment with atenolol for 5.5 years. No treatment only follow up. | 9 | 826 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Who Have Required Renal Replacement Therapy (Dialysis or Kidney Transplant) Since the End of the ASCOT Trial
- Description
- Number of participants who have required renal replacement therapy (dialysis or kidney transplant) since the end of the ASCOT trial, follow up
- Time frame
- 16 years
- Population
- 18 participants had missing data
Source ClinicalTrials.gov
Trial
- Title
- Anglo-Scandinavian Cardiac Outcomes Trial: Post Trial Follow-Up Study
- NCT number
- NCT01499511
- Phases
- Conditions
- Hypertension, Diabetes, Death From Cardiovascular Disease, Myocardial Infarction, Stroke
- Interventions
- Lead sponsor
- Imperial College London
- Results first posted
- 2019-12-03
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01499511?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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