Comparison · NCT01499511-32241691
ASCOT Participants Amlodipine vs ASCOT Participants Atenolol: Number of Participants Who Have Developed Diabetes Since the End of the ASCOT Trial
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. ASCOT Participants Amlodipine vs ASCOT Participants Atenolol: Number of Participants Who Have Developed Diabetes Since the End of the ASCOT Trial. Trial comparisons, record NCT01499511-32241691. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01499511-32241691
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.37 | 0.338 | 0.402 | wilson | |
| Risk in group 2 | 0.394 | 0.361 | 0.428 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0242 | -0.0704 | 0.022 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.938 | 0.831 | 1.06 | log | |
| Odds ratio, group 1 over group 2 | 0.902 | 0.742 | 1.1 | log | |
| Number needed to treat, for one fewer participant with the outcome on ASCOT Participants Amlodipine than on ASCOT Participants Atenolol | 41.2 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | ASCOT Participants Amlodipine | It is follow up group from the ASCOT study, after treatment with amlodipine for 5.5 years. No treatment only follow up. | 322 | 871 | OG000 |
| Group 2 | ASCOT Participants Atenolol | It is follow up group from the ASCOT study, after treatment with atenolol for 5.5 years. No treatment only follow up. | 325 | 825 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Who Have Developed Diabetes Since the End of the ASCOT Trial
- Description
- Diabetes morbidity after 16 years in patients recruited into the Anglo-Scandinavian Outcomes trial
- Time frame
- 16 years
- Population
- 22 participants had missing data
Source ClinicalTrials.gov
Trial
- Title
- Anglo-Scandinavian Cardiac Outcomes Trial: Post Trial Follow-Up Study
- NCT number
- NCT01499511
- Phases
- Conditions
- Hypertension, Diabetes, Death From Cardiovascular Disease, Myocardial Infarction, Stroke
- Interventions
- Lead sponsor
- Imperial College London
- Results first posted
- 2019-12-03
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01499511?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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