Comparison · NCT01585441-c80d910d
Finasteride 5 mg vs Placebo: Number of Participants Presenting No Change in Fluid Leakage at the Safety Visit Compared to Baseline
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Finasteride 5 mg vs Placebo: Number of Participants Presenting No Change in Fluid Leakage at the Safety Visit Compared to Baseline. Trial comparisons, record NCT01585441-c80d910d. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01585441-c80d910d
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.667 | 0.208 | 0.939 | wilson | |
| Risk in group 2 | 1 | 0.342 | 1 | wilson | |
| Risk difference, group 1 minus group 2 | -0.333 | -0.792 | 0.378 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.667 | 0.3 | 1.48 | log | |
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one fewer participant with the outcome on Finasteride 5 mg than on Placebo | 3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Finasteride 5 mg | Participants randomly assigned to the finasteride 5 mg arm were instructed to take one capsule daily for three months.~Finasteride: Finasteride is available as white, round 5 mg tablets. During the masked period, the tablets are re-formulated in capsules with inactive ingredients. The re-formulated finasteride capsules are indistinguishable from the placebo capsules. | 2 | 3 | OG000 |
| Group 2 | Placebo | Participants randomly assigned to the placebo arm will instructed to take one capsule daily for three months.~Placebo: Capsule with no active ingredients to mimic finasteride | 2 | 2 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Presenting No Change in Fluid Leakage at the Safety Visit Compared to Baseline
- Description
- Changes in leakage as observed on fluorescein angiography (FA)
- Time frame
- Final Study Visit
- Population
Source ClinicalTrials.gov
Trial
- Title
- Finasteride for Chronic Central Serous Chorioretinopathy
- NCT number
- NCT01585441
- Phases
- PHASE2
- Conditions
- Retinal Disease
- Interventions
- Finasteride, Placebo
- Lead sponsor
- National Eye Institute (NEI)
- Results first posted
- 2014-12-04
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01585441?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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