Comparison · NCT01602068-977bb53d
Dexamethasone Phosphate Ophthalmic vs 100 mM Sodium Citrate Buffer: Percentage of Subjects With AC Cell Count of Zero on Day 7
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Dexamethasone Phosphate Ophthalmic vs 100 mM Sodium Citrate Buffer: Percentage of Subjects With AC Cell Count of Zero on Day 7. Trial comparisons, record NCT01602068-977bb53d. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01602068-977bb53d
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.13 | 0.0454 | 0.321 | wilson | |
| Risk in group 2 | 0.0909 | 0.0253 | 0.278 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0395 | -0.166 | 0.241 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.43 | 0.264 | 7.78 | log | |
| Odds ratio, group 1 over group 2 | 1.5 | 0.226 | 9.96 | log | |
| Number needed to treat, for one more participant with the outcome on Dexamethasone Phosphate Ophthalmic than on 100 mM Sodium Citrate Buffer | 25.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Dexamethasone Phosphate Ophthalmic | Dexamethasone Phosphate Ophthalmic: (40 mg/mL) solution delivered by transcleral iontophoresis consisting of 4.0 mA-min at 1.5 mA on Day -1 (the day before cataract surgery) | 3 | 23 | OG000 |
| Group 2 | 100 mM Sodium Citrate Buffer | Placebo (100 mM sodium citrate buffer solution) delivered by transcleral iontophoresis consisting of 4.0 mA-min at 1.5 mA on Day -1 (the day before cataract surgery) | 2 | 22 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Percentage of Subjects With AC Cell Count of Zero on Day 7
- Description
- Percentage of patients with anterior chamber (AC) cell count of zero on Day 7 as compared between the active and placebo groups
- Time frame
- At Day 7 (plus or minus two days) following the study treatment
- Population
- This was an exploratory study and therefore a number of efficacy and safety parameters were evaluated. In all measures there was no significant difference between the active and non-active arms.
Source ClinicalTrials.gov
Trial
- Title
- Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
- NCT number
- NCT01602068
- Phases
- PHASE2
- Conditions
- Cataract
- Interventions
- Dexamethasone Phosphate Ophthalmic, 100 mM Sodium Citrate Buffer
- Lead sponsor
- Eyegate Pharmaceuticals, Inc.
- Results first posted
- 2018-05-21
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01602068?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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