Comparison · NCT01610206-deaths
Gemcitabine vs Gemcitabine + Pazopanib: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Gemcitabine vs Gemcitabine + Pazopanib: deaths from any cause. Trial comparisons, record NCT01610206-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01610206-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.74 | 0.629 | 0.827 | wilson | |
| Risk in group 2 | 0.84 | 0.741 | 0.906 | wilson | |
| Risk difference, group 1 minus group 2 | -0.1 | -0.229 | 0.0315 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.881 | 0.744 | 1.04 | log | |
| Odds ratio, group 1 over group 2 | 0.541 | 0.241 | 1.22 | log | |
| Number needed to treat, for one fewer death from any cause on Gemcitabine than on Gemcitabine + Pazopanib | 9.97 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Gemcitabine | Gemcitabine: Patients will receive gemcitabine 1000 mg/m2 administered weekly on days 1 and 8 (30 minutes IV infusion) of each cycle for up to 6 cycles. Each cycle is 21 days. | 54 | 73 | EG000 |
| Group 2 | Gemcitabine + Pazopanib | Gemcitabine: Patients will receive gemcitabine 1000 mg/m2 administered weekly on days 1 and 8 (30 minutes IV infusion) of each cycle for up to 6 cycles. Each cycle is 21 days.~pazopanib: Patients will receive pazopanib 800mg PO daily on days 1-21 of treatment cycles | 63 | 75 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Adverse events were collected from the time the first study-related procedure was performed until 30 days post administration of the last study treatment.
Source ClinicalTrials.gov
Trial
- Title
- A Randomized Study of Safety and Efficacy of Pazopanib and Gemcitabine in Persistent or Relapsed Ovarian Cancer
- NCT number
- NCT01610206
- Phases
- PHASE2
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Interventions
- Gemcitabine, pazopanib
- Lead sponsor
- Linda R Duska
- Results first posted
- 2021-02-25
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01610206?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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