Comparison · NCT01717742-ebad0ebd
Intervention vs Control: Number of Participants With Hospital Readmission
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Intervention vs Control: Number of Participants With Hospital Readmission. Trial comparisons, record NCT01717742-ebad0ebd. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01717742-ebad0ebd
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0408 | 0.0113 | 0.137 | wilson | |
| Risk in group 2 | 0 | 0.00000000000000000694 | 0.0741 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0408 | -0.039 | 0.137 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one more participant with the outcome on Intervention than on Control | 24.5 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intervention | Intervention group received intrapleural tPA, 4 mg, followed by DNase (Roche), 5 mg | 2 | 49 | OG000 |
| Group 2 | Control | Control group received intrapleural tPA (Roche), 4 mg, followed by 5 mL of normal saline | 0 | 48 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Hospital Readmission
- Description
- Number of Participants who had any hospital readmission after discharge from hospital for initial treatment for pleural empyema within three months related to pleural empyema or its treatment.
- Time frame
- 3 months post-discharge
- Population
Source ClinicalTrials.gov
Trial
- Title
- Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial)
- NCT number
- NCT01717742
- Phases
- PHASE3
- Conditions
- Pleural Empyema
- Interventions
- TPA (Tissue Plasminogen Activator), DNase, Placebo
- Lead sponsor
- The Hospital for Sick Children
- Results first posted
- 2020-04-03
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01717742?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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