Comparison · NCT01741259-9d62ecd0
Meperidine PCEA vs Meperidine PCEA With Basal: Pruritus
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Meperidine PCEA vs Meperidine PCEA With Basal: Pruritus. Trial comparisons, record NCT01741259-9d62ecd0. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01741259-9d62ecd0
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.157 | 0.104 | 0.231 | wilson | |
| Risk in group 2 | 0.0775 | 0.0426 | 0.137 | wilson | |
| Risk difference, group 1 minus group 2 | 0.08 | 0.000317 | 0.161 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.03 | 0.99 | 4.17 | log | |
| Odds ratio, group 1 over group 2 | 2.22 | 0.997 | 4.96 | log | |
| Number needed to treat, for one more participant with the outcome on Meperidine PCEA than on Meperidine PCEA With Basal | 12.5 | 6.21 | 3,160 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Meperidine PCEA | Epidural Meperidine (5mg/ml) bolus of 20 mg, lockout of 30 min, hourly limit of 50 mg.~Meperidine | 20 | 127 | OG000 |
| Group 2 | Meperidine PCEA With Basal | Epidural meperidine (5mg/ml) basal rate of 10 mg/hr, bolus 20 mg, lockout 30 min, hourly limit 40 mg~Meperidine | 10 | 129 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Pruritus
- Description
- The incidence of pruritus will be estimated by the administration of diphenhydramine or nalbuphine during the study period as recorded in the patient record.
- Time frame
- 36-48 hours post-op (until the epidural is stopped)
- Population
Source ClinicalTrials.gov
Trial
- Title
- A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus
- NCT number
- NCT01741259
- Phases
- NA
- Conditions
- Cesarean Section
- Interventions
- Meperidine
- Lead sponsor
- Mercy Research
- Results first posted
- 2017-10-25
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01741259?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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