Comparison · NCT01754909-4e8198a0
Enalapril vs Placebo: Number of Participants With Radiation Pneumonitis by CT Scan
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Enalapril vs Placebo: Number of Participants With Radiation Pneumonitis by CT Scan. Trial comparisons, record NCT01754909-4e8198a0. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01754909-4e8198a0
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.8 | 0.584 | 0.919 | wilson | |
| Risk in group 2 | 0.571 | 0.365 | 0.755 | wilson | |
| Risk difference, group 1 minus group 2 | 0.229 | -0.0551 | 0.467 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.4 | 0.91 | 2.15 | log | |
| Odds ratio, group 1 over group 2 | 3 | 0.743 | 12.1 | log | |
| Number needed to treat, for one more participant with the outcome on Enalapril than on Placebo | 4.37 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Enalapril | Use of enalapril in subjects undergoing radiotherapy for lung cancer.~Enalapril: Enalapril once a day, orally, as 2.5 , 5, or 10 mg tablets to be given in escalating doses, to subjects undergoing radiotherapy for lung cancer | 16 | 20 | OG000 |
| Group 2 | Placebo | Use of placebo in subjects undergoing radiotherapy for lung cancer~placebo: Placebo, once a day, orally, as 2.5 , 5, or 10 mg tablets to be given in escalating doses, to subjects undergoing radiotherapy for lung cancer | 12 | 21 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Radiation Pneumonitis by CT Scan
- Description
- The occurrence and grade of radiation pneumonitis by radiographic criteria, using CT scanning
- Time frame
- six months
- Population
- analyzed by CT scan readings done in a masked fashion
Source ClinicalTrials.gov
Trial
- Title
- Mitigation of Radiation Pneumonitis and Fibrosis
- NCT number
- NCT01754909
- Phases
- PHASE2
- Conditions
- Lung Cancer, Radiation Pneumonitis
- Interventions
- Enalapril, placebo
- Lead sponsor
- VA Office of Research and Development
- Results first posted
- 2019-10-01
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01754909?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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