Comparison · NCT01756846-1b14404c
HEART Care vs Usual Care: MACE (Major Adverse Cardiac Events)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. HEART Care vs Usual Care: MACE (Major Adverse Cardiac Events). Trial comparisons, record NCT01756846-1b14404c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01756846-1b14404c
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.189 | 0.172 | 0.208 | wilson | |
| Risk in group 2 | 0.222 | 0.203 | 0.241 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0322 | -0.0584 | -0.00599 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.855 | 0.752 | 0.971 | log | |
| Odds ratio, group 1 over group 2 | 0.821 | 0.699 | 0.964 | log | |
| Number needed to treat, for one fewer participant with the outcome on HEART Care than on Usual Care | 31 | 17.1 | 167 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | HEART Care | HEART care: usual care, complemented by calculation of the HEART score and following the recommended policy. | 345 | 1,821 | OG001 |
| Group 2 | Usual Care | usual care was defined as daily practice of the cardiologist or attending emergency doctor, in order to diagnose a patient with chest pain. In this period attending doctors assess the risk of a patient with chest pain, based on his/hers experience and various criteria (for example described in European Society of Cardiology Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation, without a formal risk score). | 405 | 1,827 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- MACE (Major Adverse Cardiac Events)
- Description
occurrence of major adverse cardiac events (MACE, i.e. acute myocardial infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Grafting (CABG) or death) within 6 weeks after presentation
- Time frame
- 6 weeks
- Population
Source ClinicalTrials.gov
Trial
- Title
- Impact on Management of the HEART Risk Score in Chest Pain Patients
- NCT number
- NCT01756846
- Phases
- NA
- Conditions
- Chest Pain
- Interventions
- usual care, use of HEART risk score
- Lead sponsor
- UMC Utrecht
- Results first posted
- 2019-01-25
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01756846?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT01756846-1b14404c