Comparison · NCT01778634-75eff08e
Azithromycin vs Placebo (5% Dextrose): Number of Participants With Death or Neurodevelopmental Impairment
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Azithromycin vs Placebo (5% Dextrose): Number of Participants With Death or Neurodevelopmental Impairment. Trial comparisons, record NCT01778634-75eff08e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01778634-75eff08e
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.472 | 0.344 | 0.603 | wilson | |
| Risk in group 2 | 0.327 | 0.215 | 0.462 | wilson | |
| Risk difference, group 1 minus group 2 | 0.145 | -0.0415 | 0.317 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.44 | 0.89 | 2.34 | log | |
| Odds ratio, group 1 over group 2 | 1.84 | 0.833 | 4.06 | log | |
| Number needed to treat, for one more participant with the outcome on Azithromycin than on Placebo (5% Dextrose) | 6.91 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Azithromycin | Azithromycin intravenous (2 mg/ml) 20 mg/kg every 24h x 3 days~Azithromycin: Azithromycin intravenous 20 mg/kg every 24 h x 3 days | 25 | 53 | OG001 |
| Group 2 | Placebo (5% Dextrose) | Placebo~Placebo: D5W 10 ml/kg every 24 h x 3 days | 17 | 52 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Death or Neurodevelopmental Impairment
- Description
Neurodevelopmental impairment will be assigned if any of the following are present at 22-26 months adjusted age: moderate to severe cerebral palsy, bilateral blindness, bilateral hearing impairment requiring amplification, Gross Motor Function Classification System score ≥ 2, or Bayley Scale of Infant and Toddler Development, 3rd edition (BSID-III) cognitive or motor score \<70.
- Time frame
- 22-26 months
- Population
- Participants who died prior to the 22-26 months assessment timepoint and participants who were assessed for neurodevelopmental impairments
Source ClinicalTrials.gov
Trial
- Title
- Trial of Intravenous Azithromycin to Eradicate Ureaplasma Respiratory Tract Infection in Preterm Infants
- NCT number
- NCT01778634
- Phases
- PHASE2
- Conditions
- Ureaplasma Infections
- Interventions
- Azithromycin, Placebo
- Lead sponsor
- University of Maryland, Baltimore
- Results first posted
- 2018-05-17
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01778634?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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