Pre-intervention vs Post-intervention: Cumulative Incidence of ART Initiation 14 Days After Clinical Eligibility in Treatment Eligible HIV-infected Patients
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.366 | 0.355 | 0.377 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.791 | 0.779 | 0.802 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.425 | -0.441 | -0.408 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.463 | 0.447 | 0.479 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.153 | 0.14 | 0.166 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with the outcome on Pre-intervention than on Post-intervention | 2.35 | 2.27 | 2.45 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Pre-intervention | This study is stepped-wedge in design, so each clinic experienced a period of time before the intervention rolled out and then a time period after the intervention rolled out. Each clinic contributes time to both conditions. Clinics in the pre-intervention condition are giving the standard of care. | 2,585 | 7,066 | OG000 | ClinicalTrials.gov |
| Group 2 | Post-intervention | This study is stepped-wedge in design, so each clinic experienced a period of time before the intervention rolled out and then a time period after the intervention rolled out. Each clinic contributes time to both conditions. Clinics in the intervention (post-intervention) have experienced training, ongoing feedback and have the PIMA machine. | 3,753 | 4,747 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Cumulative Incidence of ART Initiation 14 Days After Clinical Eligibility in Treatment Eligible HIV-infected Patients | ClinicalTrials.gov |
| Description | Patients may be ART eligible at the start of the study or become ART eligible for the first time in the 3 year time frame. | ClinicalTrials.gov |
| Time frame | 14 days | ClinicalTrials.gov |
| Population | Persons who did have the opportunity for 14 days of follow up were excluded from these analyses. | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | The "START" (a Streamlined ART Initiation Strategy) Study | ClinicalTrials.gov |
| NCT number | NCT01810289 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | HIV | ClinicalTrials.gov |
| Interventions | START | ClinicalTrials.gov |
| Lead sponsor | University of California, San Francisco | ClinicalTrials.gov |
| Results first posted | 2017-02-27 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT01810289?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.