Comparison · NCT01823328-58ec173b
Ketamine vs Etomidate: Number of Patients With First-pass Success
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Ketamine vs Etomidate: Number of Patients With First-pass Success. Trial comparisons, record NCT01823328-58ec173b. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01823328-58ec173b
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.952 | 0.867 | 0.983 | wilson | |
| Risk in group 2 | 0.896 | 0.8 | 0.948 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0561 | -0.0436 | 0.157 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.06 | 0.962 | 1.17 | log | |
| Odds ratio, group 1 over group 2 | 2.29 | 0.566 | 9.3 | log | |
| Number needed to treat, for one more participant with the outcome on Ketamine than on Etomidate | 17.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ketamine | Subjects in the ketamine arm will receive ketamine for sedation prior to rapid sequence intubation (RSI).~Ketamine: Subjects will receive ketamine for sedation prior to rapid sequence intubation. | 59 | 62 | OG000 |
| Group 2 | Etomidate | Subjects in the etomidate arm will receive etomidate for sedation prior to rapid sequence intubation (RSI).~Etomidate: Subjects will receive etomidate for sedation prior to rapid sequence intubation. | 60 | 67 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Patients With First-pass Success
- Description
The rate of first pass success, defined as successful tracheal intubation on the first attempt. An attempt is defined as the insertion and subsequent removal of the laryngoscopic device from the patient's mouth, regardless of whether an endotracheal tube was inserted.
- Time frame
- up to 5 minutes (average time frame)
- Population
Source ClinicalTrials.gov
Trial
- Title
- Ketamine Versus Etomidate for Rapid Sequence Intubation
- NCT number
- NCT01823328
- Phases
- PHASE4
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Interventions
- Ketamine, Etomidate
- Lead sponsor
- Hennepin Healthcare Research Institute
- Results first posted
- 2019-05-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01823328?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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