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Comparison · NCT01832259-deaths

Pazopanib Arm vs Placebo Arm: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Pazopanib Arm vs Placebo Arm: deaths from any cause. Trial comparisons, record NCT01832259-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01832259-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 1000.204wilson
Risk in group 2000.204wilson
Risk difference, group 1 minus group 20-0.2040.204newcombe hybrid score
Risk ratio, group 1 over group 2loga group has no participants with the outcome
Odds ratio, group 1 over group 2loga cell of the two-by-two table is zero
Number needed to harmfrom the risk difference intervalthe two groups' risks are equal

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Pazopanib ArmParticipants receiving Pazopanib~Pazopanib: Pazopanib, 800 mg, orally daily for 28 days prior to radical prostatectomy.015EG001
Group 2Placebo ArmParticipants receiving placebo~Placebo: Placebo tablet orally, daily for 28 days prior to radical prostatectomy.015EG000

Harm

What it counts
Total, all-cause mortality
Time frame
Adverse events were collected for approximately 2 months (from first dose of study medication to 1 month post-prostatectomy).

Source ClinicalTrials.gov

Trial

Title
A Study of VEGF Tyrosine Kinase Inhibitor (Pazopanib) in Men With High-Risk Prostate Cancer Followed by Radical Prostatectomy and Pelvic Lymph Node Dissection
NCT number
NCT01832259
Phases
PHASE2
Conditions
Adenocarcinoma of the Prostate
Interventions
Pazopanib, Placebo
Lead sponsor
University of Utah
Results first posted
2018-06-12

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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